Select prior publications
Chen C, Yu W, Alikarami F, Qiu Q, Chen CH, Flournoy J, Gao P, Uzun Y, Fang L, Davenport JW, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Felix CA, Wu H, Brown PA, Guest EM, Barrett DM, Bernt KM, Tan K. Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia. Blood. 2022 Apr 7;139(14):2198–2211. PMCID: PMC8990373
Ding YY, Kim H, Madden K, Loftus JP, Chen GM, Hottman Allen D, Zhang R, Xu J, Chen C-H, Hu Y, Tasian SK, Tan K. Network Analysis Reveals Rational Combination Therapy Targets in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia. Clin Cancer Res. 2021 Jul 1. PMCID: PMC8448976.
Hu Y, Chen C, Ding YY, Wen X, Wang B, Gao L, Tan K. Optimal control nodes in disease-perturbed networks as targets for combination therapy. Nat Commun. 2019. PMCID: PMC6522545.
He B, Gao P, Ding YY, Chen C, Chen GM, Chen C, Kim H, Tasian SK, Hunger SP, Tan K. Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers. Science Advances. 2020 Jul 24;6(30). PMCID: PMC7439310.
Ding YY, Stern JW, Jubelirer TF, Wertheim GB, Li F, Chang F, Gu Z, Mullighan CG, Li Y, Harvey RC, Chen IM, Willman CL, Hunger SP, Li MM, and Tasian SK. Clinical efficacy of ruxolitinib and chemotherapy in a child with Philadelphia chromosome-like acute lymphoblastic leukemia with GOLGA5-JAK2 fusion and induction failure. Haematologica. 2018. 103(9):e427-e431. PMCID: PMC6119161.
Chen GM, Chen C, Das RK, Gao P, Chen CH, Bandyopadhyay S, Ding YY, Uzun Y, Yu W, Zhu Q, Myers RM, Grupp SA, Barrett DM, Tan K. Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy. Cancer Discov 2021;11:2186–99. PMCID: PMC8419030.
Chen GM, Azzam A, Ding YY, Barrett DM, Grupp SA, Tan K. Dissecting the Tumor-Immune Landscape in Chimeric Antigen Receptor T-cell Therapy: Key Challenges and Opportunities for a Systems Immunology Approach. Clin Cancer Res 2020;26:3505–13. PMCID: PMC7367708.
